Vydura 75mg for Migraine Prevention 16 Tablets

What is Vydura 75mg for migraine prevention and how does it work?

Vydura 75mg is a prescription-only medication suitable for the prevention of migraine with or without aura (1). The active ingredient is Rimegepant.

Vydura works by blocking a signal in the brain called calcitonin gene-related peptide (CGRP) which is involved in starting migraines. When a migraine starts, CGRP is released by nerve cells, causing inflammation that sends signals that tells the brain it’s experiencing pain. Rimegepant is a CGRP inhibitor that stops this happening, so migraine attacks are less likely to start (3).

It doesn’t work in the same way as pain medications, which help to lower the effects of migraines once they have already started.

Who is Vydura 75mg for migraine prevention suitable for?

Vydura 75mg may be suitable for adults (18+) who (4):

• Experience regular migraines (approximately 4 to 15 per month)
• Have tried other types of treatment, including triptan medications like sumatriptan, without success
• Have tried over the counter pain medication without success
• Have had a diagnosis of chronic migraine by a migraine specialist

Who is Vydura 75mg for migraine prevention not suitable for?

Vydura 75mg for migraine prevention is not suitable for anyone who (4):

• Is under the age of 18
• Is allergic to any of the ingredients (see the Patient Information Leaflet for details)
• Has severe liver problems
• Has reduced kidney function or is on kidney dialysis
• Is pregnant or breastfeeding (unless otherwise advised)

The safety of Vydura 75mg in pregnancy or while breastfeeding has not been studied. If you are pregnant, breastfeeding or planning on either, speak to your prescriber before starting Vydura.

How is Vudyra for migraine prevention different from Vydura acute treatment?

Vydura is a unique medication in that it can be used both to reduce the likelihood of migraines in people who experience regular episodes, and to treat active migraines. The difference lies in the timing with which the medication is taken.

• In acute treatment, Vydura is taken as soon as you feel a migraine coming on.
• In preventative treatment, Vydura is taken every other day, even if no migraine is present.

In both cases, it blocks the CGRP receptor. However, acute use aims for symptom relief during a single episode, while preventative use aims to gradually quieten the migraine system over time to lower attack frequency (3).

The importance of migraine prevention

Migraine prevention can be more important than reacting once an attack has started because it helps reduce the number of days spent in pain, missing work, avoiding plans, or relying on rescue medication. Vydura is designed to help lower the likelihood of migraine attacks before they take hold (2), which can mean less disruption to everyday life and a greater sense of control over the condition. For many people, preventing attacks is not just about avoiding pain in the moment, but about protecting time, routine, and quality of life.

What results can I expect?

Vydura is proven to be successful in reducing episodes of migraine. When taken every other day, clinical trials show that it safely reduces monthly migraine days, with around 49% of people stating their monthly migraine days dropped by 50% or more (8).